Romans Chapter 1 Vs. 28

God's Wrath on Unrighteousness

And even as they did not like to retain God in their knowledge, God gave them over to a reprobate mind, to do those things which are not convenient; Rom 1:28

God gave them... Three things God gave them up:

1. To dishonor their bodies (Rom. 1:24).

2. To vile affections in their souls (Rom. 1:26).

3. To reprobate minds (Rom. 1:28).

reprobate... Greek: adokimos, reprobate (Rom. 1:28; 2Cor. 13:5, 13:6, 13:7; 2Tim. 3:8; Tit. 1:16); rejected (Heb. 6:8); and castaway (1Cor. 9:27). Christ is not in reprobates.

Convenient... Greek: katheko, fit; proper (Acts 22:22).

Abandoned to depraved lifestyle

Pagan humanity’s rebellion also included the rejection of the knowledge (epignōsei, “full knowledge”; cf. Rom. 1:32) of God. In a sense they put God out of their minds. God’s responding judgment was abandonment (cf. Rom. 1:24, 1:26) to a depraved (adokimon, “disapproved”) mind, which expressed itself in attitudes and actions that ought not to be done (lit., “what is unfitting or improper,” a technical Stoic word). Reprobate or debased mind, in the sense it is used here, means (worthless, castaway, or rejected). Debased translates a Greek word that means “not passing the test.” It was often used to describe useless, worthless metals, discarded because they contained too much impurity. God has tested some mans’ minds and found them worthless and useless.

God has turned away from this type person, because they have rejected God and all His teachings. I believe it is possible for a homosexual or lesbian to be saved, but only if they walk away from their old life. I do not believe a person practicing homosexuality or lesbianism is saved. Things which are not convenient: means against nature.

Verse 28 is saying that the Holy Spirit stops pursuing them for salvation.